1. Local damage

For small and mobile stones, the damage of local tissue is only slight; large and antler like stones will produce fibrous tissue proliferation, neutrophils, ulcers and lymphocytic infiltration, leading to renal fibrosis and epithelial cell exfoliation of renal pelvis and calyx.

2. Kidney damage

Long term renal calculi will have hydronephrosis, dysuria, excessive pressure on the upper part of obstruction, decreased renal blood flow, which will lead to renal atrophy, decreased renal function, necrosis of renal tubules, and even loss of renal function.

3. Urinary obstruction

Urinary tract obstruction is not only the main factor of secondary renal damage, but also the most common secondary renal stone damage. The symptoms of water accumulation in the upper part of urinary tract obstruction will appear. Renal calculi can lead to excessive pressure, hydronephrosis, obstruction of urination and decrease of renal blood flow.

For the common disease of kidney stone, its harm is very huge. The kidney is a very important internal organ of the body. It is not allowed to have any small problems. Because the levee of thousands of miles is destroyed in the ant nest, and it's not cold in a day. Patients still have to go to a professional hospital to treat the disease thoroughly. Urolithiasis can be seen in any part of kidney, bladder, ureter and urethra, which is one of the common urological diseases. After urinary tract stones cause urinary tract obstruction and infection, the renal function is seriously damaged, the whole body is more seriously affected and life-threatening. Hospital experts said: Generally speaking, stones smaller, less than 4 mm in general can be discharged by drug treatment, and more than 6 mm in less chance of self discharge, the higher the stone position, the smaller the chance of discharge, it is recommended to use minimally invasive surgery.